Research, News, & Links
Scientific Research
NMDAR inhibition-independent antidepressant actions of ketamine metabolites (PDF)
Efficacy of Intravenous Ketamine for Treatment of Chronic Posttraumatic Stress Disorder.
Synaptic Dysfunction in Depression: Potential Therapeutic Targets
Safety and Efficacy of Repeated-Dose Intravenous Ketamine for Treatment-Resistant Depression
Maintenance Ketamine Treatment Produces Long-term Recovery from Depression
NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses
A Randomized Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Major Depression
Ketamine as a novel antidepressant: from synapse to behavior
Serial infusions of low-dose ketamine for major depression (abstract)
Neurobiological advances identify novel antidepressant targets
The role of AMPA receptor modulation in the treatment of neuropsychiatric diseases
Synaptic function in depression: potential therapeutic targets
Efficacy of Intravenous Ketamine for Treatment of Chronic Posttraumatic Stress Disorder
NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses
Signaling Pathways Underlying the Rapid Antidepressant Actions of Ketamine
Antidepressant effects of ketamine: mechanisms underlying fast-acting novel antidepressants
In the News
Bloomberg (2015) http://www.bloomberg.com/graphics/2015-ketamine-depression-treatment/
Nature (2015) http://www.nature.com/news/rave-drug-holds-promise-for-treating-depression-fast-1.16664
VICE News (2015) https://www.vice.com/read/i-used-ketamine-to-treat-my-depression-122
NY Times (2014) http://www.nytimes.com/2014/12/10/business/special-k-a-hallucinogen-raises-hopes-and-concerns-as-a-treatment-for-depression.html?_r=0
Scientific American (2013) http://www.scientificamerican.com/article/is-ketamine-next-big-depression-drug/
Time (2013) http://healthland.time.com/2013/05/22/club-drug-ketamine-lifts-depression-in-hours/
Psychology Today (2016) A New Medication on the Horizon for Depression
Neurology Advisor (2016) Ketamine May Be Effective in Major Depression
Psychiatry Advisor (2016) May Provide Lasting Relief From Depression
PRNewswire (2016) New Study Shows Ketamine May Regenerate Brain Cells, Relieving Depression with Lasting Benefit
New York Magazine (2016) What It’s Like to Have Your Severe Depression Treated With a Hallucinogenic Drug,
Nature.com Rave drug holds promise for treating depression fast
Economist.com – Novel drugs for depression
NPR.com Ketamine Relieves Depression By Restoring Brain Connections
National Institutes of Mental Health Rapid Antidepressant Works by Boosting Brain’s Connections
CurrentPsychiatry.com The future of ketamine in psychiatry
PsychiatricNews.com Ketamine-Induced Optimism: New Hope for the Development of Rapid-Acting Antidepressants
TheAtlantic.com ‘The Biggest Breakthrough in Depression Research’ in 50 Years Is … Ketamine?
J&J Press Release Esketamine Receives Breakthrough Therapy Designation from U.S. Food and Drug Administration for Major Depressive Disorder with Imminent Risk for Suicide
CNN.com Party drug ketamine closer to approval for depression
Nature.com How club drug ketamine fights depression
NPR.com Depression Treatments Inspired By Club Drug Move Ahead In Tests
Media
VIDEO on PBS – Dr. Carlos Zarate Documentary about Depression
VIDEO on ABC News – Party Drug to Treat Depression?
VIDEO on PBS – Dr. Carlos Zarate Documentary about Depression
ChicagoTribune.com – Once-popular party drug now used for severe depression
NBCNews.com – ‘Club Drug’ Ketamine Rescues Suicidal Patients
NYPost.com – A Party Drug Instantly Cured My Depression
Vice.com – How Ketamine Infusions Saved My Life